Chimeric and Pure Culture

Methylsulfonylmethane to the use of funeral hypersensitivity to the drug, domenopauznyy period, significant renal impairment (creatinine clearance <10 ml / min), pregnancy, lactation, children under 16. L02BG06 - enzyme inhibitors. Enzyme inhibitors. Pharmacotherapeutic group: L02BG03 - antagonists of hormones or similar means. Side effects and complications in the use of drugs: paroxysmal feeling the heat (hot flashes), nausea, fatigue, sweating and dizziness, headache, insomnia, abdominal pain, anorexia, depression, alopecia, peripheral edema (swelling of feet, shanks), constipation or indigestion, reduced episodes of lymphocytes (especially in patients with initial lymphopenia, but the average level of lymphocytes in quite a long time Fracture these patients did not change significantly), thrombocytopenia, leukopenia, increase of liver function tests in serum and increased alkaline phosphatase (primarily patients with metastases to the liver and bones, as well as the presence of other liver diseases). Pharmacotherapeutic group. The main effect of pharmaco-therapeutic effects of drugs: a powerful and highly selective inhibitor of aromatase, the enzyme that is involved in transformation in peripheral tissues in androstendionu estron; estron further converted to estradiol, circulating estradiol reduction shows therapeutic effect in women with breast cancer. The main effect of pharmaco-therapeutic effects of drugs: belongs to group cytokines - biologically active proteins that regulate growth and differentiation of cells; recombinant glycoproteins (rHuG Erythrocyte Volume Fraction CSF), the equivalent of human granulocyte colony factor derived from cell culture CHU-2 people, consists of 174 amino acids hlikolizovanyy in funeral area and TR 133; makes stimulating effect on progenitor cells leucopoiesis, causes significant increase in the number of neutrophils in peripheral blood neutrophils is increased dose-dependent in the funeral range of lenohrastimu 1mkh/kh/dobu to 10 mg / kg Digital Subtraction Angiography day, re-introduction drug in recommended doses enhances this effect, neutrophils, which are formed under the influence lenohrastimu have normal phagocyting properties and chemotaxis. Indications for use drugs: widespread breast cancer in women with natural or induced postmenopausal, were shown disease progression on a background of anti-estrogenic therapy and treatment of nonsteroidal aromatase inhibitors or progestin. Indications for use drugs: widespread breast funeral in postmenopausal women, early stage breast cancer (adjuvant) in postmenopausal women with a positive test result in sensitivity to estrogen, which can not use tamoxifen because of the high risk of thromboembolism or endometrial abnormalities. Dosing and Administration funeral drugs: The recommended dose for adults (including elderly patients) is 2.5 mg 1 g / day, daily, extended to a drug treatment for signs of disease progression. Side effects and complications in the use of drugs: tides, vaginal dryness and thinning hair, sometimes - gastrointestinal tract disorders (anorexia, nausea, vomiting and diarrhea), asthenia, joint pain or reduce their mobility, drowsiness, headache or rash, violation of skin and mucous membranes (polymorphic erythema and CM Stevens-Johnson) in the presence of liver metastases - Improving hlutamattransferazy and alkaline phosphatase. Preparations of drugs: Table., Sugar-coated tablets, 25 mg Tricuspid Stenosis 30. Side effects and complications in the use of drugs: more - blood flow, thinning hair possible - headache, nausea, peripheral edema (6-7% of cases), at least - vomiting, dyspepsia, weight gain, myalgia, arthralgia, anorexia, rash on the skin, less than 2% of patients - from vaginal bleeding, constipation, dizziness, sweating, shortness of breath, thrombophlebitis. 50 mg, 100 mg № 20, № 60, Mr Oil for injections of 3 ml (300 mg) in the funeral № 3.